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<font face="Arial"><i><b>The effect of treatment on quality of life in psoriasis 
patients.</b></i></font></p>
<p style="margin-left: 10"><b><font face="Arial" size="2">Prins M, Krabbe PF, 
Swinkels QO, de Boo T, van de Kerkhof PC, van der Valk PG.</font></b></p>
<p style="margin-left: 10"><font face="Verdana" size="2">Department of 
Dermatology, Radboud University Nijmegen Medical Centre, The Netherlands. 
M.Prins@derma.umcn.nl<br>
<br>
Psoriasis is a chronic skin disease with substantial impact on patients' social 
and relational ways of living and subsequently on their quality of life. The aim 
of this study was to evaluate the health-related quality of life (HRQoL) of 
patients with moderate to severe psoriasis treated with short contact dithranol 
treatment, UVB phototherapy or inpatient dithranol treatment. HRQoL was 
evaluated in an open randomized multicentre study by appliance of the Dutch 
short form of the Sickness Impact Profile and the Psoriasis Disability Index; 
250 patients were included. Successful short contact dithranol treatment and UVB 
phototherapy both led to a comparable improvement in HRQoL immediately after 
treatment until the end of the follow-up (maximum 1 year). Inpatients 
experienced a more impaired HRQoL and showed no significant improvement in HRQoL 
directly following treatment. At the end of the study HRQoL became comparable 
for all treatment groups.All three treatments led to substantial improvement in 
HRQoL; however, patients treated by short contact treatment or UVB showed a 
better HRQoL than inpatients.</font></p>
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